Method for producing synthetic N-linked glycoconjugates

Details Method for producing synthetic N-linked glycoconjugates Method for producing synthetic N-linked glycoconjugates

1992-08-11

1994-01-18

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 553, 435 792, C07H 504, C12Q 100

Patent

active

052801136

ABSTRACT:
A method is disclosed for derivatizing oligosaccharides to form synthetic N-linked glycoconjugates by converting a glycosylamine derivative of the oligosaccharide to a haloacetylated derivative as an intermediate compound prior to formation of the synthetic N-linked glycoconjugate to thereby directly maintain the .beta.-anomeric configuration of said N-linked glycoconjugate.

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