Method for producing substituted nitro benzoic acids by...

Organic compounds -- part of the class 532-570 series – Organic compounds – Sulfonic acids or salts thereof

Reexamination Certificate

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C562S410000, C562S434000, C562S438000

Reexamination Certificate

active

07094923

ABSTRACT:
The present invention relates to the preparation of nitrobenzoic acids by oxidizing particular nitrotoluenes, nitrobenzyl alcohols, esters and/or ethers in the presence of nitric acid at elevated temperature and elevated pressure. It has been found that the particular nitrotoluenes, nitrobenzyl alcohols, esters and/or ethers may be oxidized particularly reliably and in high yields using nitric acid to the benzoic acid derivatives when they are metered into the nitric acid.

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Bengtsson, “Continuous High-Pressure Oxidation with Nitric Acid in a Tubular Converter” IVA (The Royal Swedish Academy of Engingeering Sciences), vol. 25(3), pp. 121-124 (1954).
Faith, Keyes and Clark's Industrial Chemicals 4thEd, pp. 563-570, John Wiley & Sons, Inc. © 1975.
Yi et al, “Synthesis of p-Nitrobenzoic Acid” Guangzhou Huagong, vol. 26(2), pp. 9-10 (1988). With English Translation.
Srinivasan and Chandalia, “Oxidation of p-Nitrotoluene to p-Nitrobenzoic Acid by Nitric Acid” Indian Journal of Technology, vol. 9(7), pp. 274-275 (1971).
Dolmatov et al, “Preparation of m-Nitrobenzoic Acid via Oxidation of m-Nitrotoluene with Diluted Nitric Acid under Pressure” Khimiko-Farmatsevticheskii Zhurnal, vol. 24(1), pp. 67-69 (1990). With English Translation.
Chemiker-Zeitung, 104, Nr. 12, (month unavailable) 1980, pp. 349-351, Von Erik Bengtsson und Boris Holm, “Oxidation mit Salpetersäure”.

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