Method for producing substance capable of stimulating differenti

Details Method for producing substance capable of stimulating differenti Method for producing substance capable of stimulating differenti

1980-07-15

1982-08-03

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

435 68, 435240, 424 99, 424101, 424115, 424177, C12N 500, C12P 1926

Patent

active

043428282

ABSTRACT:
A colony stimulating factor effective in treating human granulocytopenia is produced by cultivating monocytes and macrophages isolated from the human peripheral blood in a synthetic medium for tissue culture containing a glycoprotein isolated from human urine and capable of stimulating the formation of human granulocytes or mouse macrophages and granulocytes.

REFERENCES:
patent: 4135975 (1979-01-01), Lichtman et al.
patent: 4275056 (1981-06-01), Takaku et al.
Motoyoshi et al., Chemical Abstracts, 89:142164t, 213 (1978).
Stanley et al., Federation Proceedings, 34(13), 2272-2278 (1975).
Price et al., Biochemical Journal, 148, 209-217 (1975).
Shah et al., Blood, 50, 811-821 (1977).
Motoyoshi et al., Chemical Abstracts, 90:1931Z, 192 (1979).

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