Method for producing (R)-malic acid from maleic acid using micro

Details Method for producing (R)-malic acid from maleic acid using micro Method for producing (R)-malic acid from maleic acid using micro

1992-01-15

1993-12-14

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435232, 435822, 435911, C12P 746, C12N 988

Patent

active

052701905

ABSTRACT:
This invention relates to a method for producing (R)-malic acid comprising contacting, in a reaction medium, maleic acid with (A) a microbial maleate hydratase capable of hydrating maleic acid to form (R)-malic acid or (B) a microorganism containing the maleate hydratase, microbial maleate hydratase and a method for producing same. In accordance with the present invention (R)-malic acid with high optical purity is supplied efficiently and economically.

REFERENCES:
Hopper D. J. et al, Biochem J. 110:798-800 (1968).
Rahatekar Hi, Indian J. Biochem 5:143-4 (1968).

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