Method for producing pyruvic acid by fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435923, C12P 740, C12R 172, C12R 173

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active

049180134

ABSTRACT:
The present invention relates to a method for producing pyruvic acid.
This method consists of first producing Candida type cells at approximately 5 pH by using a culture medium comprising thiamine and then producing pyruvic acid by culturing cells at about 4 pH by using a culture medium not containing thiamine or iron. Therefore, the production of pyruvic acid (curve I) is favored by limiting the production of alpha-ketoglutaric acid (curve II).

REFERENCES:
patent: 3993543 (1976-11-01), Uchio et al.
CHEMICAL ABSTRACTS, vol. 68, No. 23, Jun. 3, 1968, p. 9920, No. 102810k, Columbus, Ohio; T. V. Finogenova et al.: KETO ACID PRODUCTION BY PARAFFINOXIDIZING YEASTS.
CHEMICAL ABSTRACTS, vol. 84, No. 25, Jun. 21, 1976, p. 420, No. 178212t, Columbus, Ohio.

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