Method for producing preparation containing bioactive substance

Details Method for producing preparation containing bioactive substance Method for producing preparation containing bioactive substance

2006-08-15

2006-08-15

Lukton, David (Department: 1654)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S468000, C424S486000, C424S044000, C424S045000, C426S425000, C264S005000

Reexamination Certificate

active

07090869

ABSTRACT:
A method for producing a preparation containing a bioactive substance, characterized in that it comprises forming a solid material containing the bioactive substance and a polymer, and contacting the solid material with a high pressure gas. The method allows the production of a preparation which is suppressed in excessive initial release of the bioactive substance immediately after the administration thereof, is capable of releasing a predetermined amount of the bioactive substance over a long period of time, and is extremely reduced in the deterioration of the bioactive substance and in the amount of a residual organic solvent.

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