Method for producing porous body comprising apatite/collagen...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.

Reexamination Certificate

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C623S011110, C623S016110, C623S023510, C623S023610, C623S023560, C427S002270, C442S411000, C442S414000, C162S003000, C156S296000

Reexamination Certificate

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07732573

ABSTRACT:
A method for producing a porous body comprising apatite/collagen composite fibers comprising the steps of gelling a dispersion comprising long apatite/collagen composite fibers having an average length of 10-75 mm, short apatite/collagen composite fibers having an average length of 0.05-1 mm, and a liquid; freezing and drying the resultant gel to form a porous body; and cross-linking collagen in the porous body.

REFERENCES:
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patent: 7153938 (2006-12-01), Kikuchi et al.
patent: 7163965 (2007-01-01), Sotome et al.
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patent: 2004/103422 (2004-12-01), None
Kikuchi et al., “Porous Body Preparation of Hydroxyapatite/Collagen Nanocomposites for Bone Tissue Regeneration,” Key Engineering Materials, vols. 254-256, pp. 561-564 (2004).
English Language abstract of JP 2005-279078.
Gelinski, M, et al., “Porous Scaffolds made from Mineralized Collagen—a Biomimetic Bone Graft Material”, Mat.-wiss. U. Werkstofftech., vol. 35, No. 4, pp. 229-233 (2004).
U.S. Appl. No. 10/599,435, filed Sep. 28, 2006.

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