Method for producing pertussis toxoid

Details Method for producing pertussis toxoid Method for producing pertussis toxoid

1982-08-16

1984-06-19

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 435 68, 260112R, A61K 3910, C07G 700, C12P 2100

Patent

active

044552971

ABSTRACT:
A pertussis toxoid is produced by removing endotoxin from a culture supernatant of a Bordetella pertussis phase I strain or a concentrate thereof and flocculating pertussis exotoxin in the resultant fluid by permitting formaldehyde to act upon the fluid in the substantial absence of basic amino acid. The thus-obtained pertussis toxoid is low in toxicity and has a high immunizing potency.

REFERENCES:
patent: 3135662 (1964-06-01), Pope et al.
patent: 4029765 (1977-06-01), Helting et al.
patent: 4033819 (1977-07-01), Helting et al.
patent: 4075321 (1978-02-01), Relyveld
patent: 4242270 (1980-12-01), Ayme et al.

Affiliated with

Also associated with

Rating

Method for producing pertussis toxoid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing pertussis toxoid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing pertussis toxoid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-413694