Method for producing organic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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Reexamination Certificate

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10976822

ABSTRACT:
A free organic acid can be produced efficiently at a low cost, by subjecting an ammonium salt of organic acid A such as a dicarboxylic acid, a tricarboxylic acid or an amino acid, to reactive crystallization with an acid B, such as a monocarboxylic acid, wherein organic acid A and acid B satisfy the following formula (1):in-line-formulae description="In-line Formulae" end="lead"?pKa(A)≦pKa(B)  (1)in-line-formulae description="In-line Formulae" end="tail"?where pKa(A) and pKa(B) represent ionization indices of organic acid A and acid B, respectively, provided that when they have plural values, they represent the minimum pKa among them, to separate free organic acid A in solid form.

REFERENCES:
patent: 3818081 (1974-06-01), Adamek
patent: 3833646 (1974-09-01), Norton
patent: 5210292 (1993-05-01), Park et al.
patent: 5958744 (1999-09-01), Berglund et al.
patent: 0 590 856 (1994-04-01), None
patent: 0 608 975 (1994-08-01), None
patent: 61-50937 (1986-03-01), None
patent: 63-264546 (1988-11-01), None

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