Method for producing optically active ester of .gamma.-substitut

Details Method for producing optically active ester of .gamma.-substitut Method for producing optically active ester of .gamma.-substitut

1996-04-10

1997-12-23

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

435135, 435911, C12P 1300, C12P 762

Patent

active

057006709

ABSTRACT:
Microbial cells and/or a preparation therefrom of a microorganism is allowed to act on an ester of .gamma.-substituted-acetoacetic acid, and a carbonyl group at its .beta.-position is stereospecifically reduced, wherein the microorganism is selected from the group consisting of those belonging to the genera Yarrowia, Filobasidium, Metschnikowia, Galactomyces, Ambrosiozyma, Trichosporonoides, Aureobasidium, Phaeococcomyces, Rosulomyces, Dothichiza, Emericellopsis, Calonectria, Colletotrichum, and Ceratocystis, preferably, the microorganism is microorganism belonging to the genus Aureobasidium. Thus an optically active ester of .gamma.-substituted-.beta.-hydroxybutyric acid having a high optical purity is produced in a short period of time at a high accumulated concentration and a high yield.

REFERENCES:
Chemical Abstracts, 104(25):223632z (1986).

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