Method for producing optically active diphosphine compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus containing

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568 13, 568 14, 568 16, 568 17, 564 15, 549220, C07F 950, C07F 902

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056938683

ABSTRACT:
The present invention provides a method for producing novel optically phosphino)-1,1'-binaphthyl compounds! having a selectivity (chemoselectivity or enantioselectivity) and catalytic activity different from those of conventional BINAP compounds. In a method of the present invention for producing an optically active diphosphine compound (i.e., 2,2-bis(di-substituted phosphino)-1,1'-binaphthyl), 2,2'-bis(trifluoromethanesulfonyloxy)-1,1'-binaphthyl is reacted, in the presence of a transition metal-phosphine complex, with a phosphineoxide compound represented by the following general formula:

REFERENCES:
Sayo, N et al "Chiral unsymemetric diphosphine compounds and transition metal complexes containing them as ligands" CA 126: 199669 (1997).

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