Method for producing optically active alcohol compound

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

Reexamination Certificate

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Reexamination Certificate

active

07728179

ABSTRACT:
A method for producing an optically active alcohol compound comprising reacting a cyclic ether compound with a phenol compound in the presence of an asymmetric complex obtained by reacting an optically active metal complex represented by the formula (1):wherein R1, R2, R3, R4, R5, R6, R7and R8are the same or different and each independently represent a hydrogen atom, an alkyl group or the like;one of R9and R10is a hydrogen group and the other is a substituted or unsubstituted phenyl group or the like;Q represents a single bond, a C1-C4 alkylene group or the like;M represents a metal ion; and when an ionic valency of the metal ion is same as a coordination number of a ligand, A is nonexistent, and when the above-mentioned ionic valency is different from the coordination number, and A represents a counter ion or a ligand, with a zirconium alkoxide or a hafnium alkoxide.

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Eric N. Jacobsen, et al., “Electronic Tuning of Asymmetric Catalysts”, J. Am. Chem. Soc., vol. 113, 1991, pp. 6703-6704.
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