Method for producing optically active 3-hydroxyhexanoic acids us

Details Method for producing optically active 3-hydroxyhexanoic acids us Method for producing optically active 3-hydroxyhexanoic acids us

1995-10-12

1997-07-01

Naff, David M.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

C12P 4100

Patent

active

056437935

ABSTRACT:
A method for producing an optically active 3-hydroxy-hexanoic acid represented by formula (1) and the enantimer by asymmetrically hydrolyzing a racemic ester of 3-hydroxyhexanoic acid in the presence of a lipase derived from porcine pancreas. ##STR1##

REFERENCES:
patent: 5128252 (1992-07-01), Miyazawa et al.
Sigma Catalog p. 611 (1992).
Bornscheuer U., Tetrahedron: Assymetry 4(5): 1007-1016 (1993).
Cambou B., Biotech. Bioengin. XXVI : 1449-54 (1984).

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