Method for producing optically active 3-chloro-2-methyl-1,...

Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...

Reexamination Certificate

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Reexamination Certificate

active

11028933

ABSTRACT:
The present invention provides a method for obtaining optically active 3-chloro-2-methyl-1,2-propanediol, the method comprising: a first step of letting at least one kind of microorganism or processed product thereof having an ability to leave untouched (R)-3-chloro-2-methyl-1,2-propanediol or (S)-3-chloro-2-methyl-1,2-propanediol in the presence of an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture act on an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture; and a second step of recovering the untouched optically active 3-chloro-2-methyl-1,2-propanediol.

REFERENCES:
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Kasai et al.,Industrialization of the Microbial Resolution of Chiral C3and C4Synthetic Units: From a Small Beginning to a Major Operation, a Personal Account, Advanced Synthesis & Catalysis, 345, No. 4, pp. 437-455, 2003.

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