Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2011-07-26
2011-07-26
Katakam, Sudhakar (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
36, 36
Reexamination Certificate
active
07985880
ABSTRACT:
There is provided a method for producing an optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl)alkylamine N-monoalkyl derivative, which includes the steps of conducting reductive alkylation of an optically active secondary amine and a formaldehyde (including an equivalent thereof) or lower aldehyde in the presence of a transition metal catalyst under a hydrogen gas atmosphere, thereby converting the secondary amine to an optically active tertiary amine of the formula, and subjecting the tertiary amine to hydrogenolysis. The target optically active compound can be produced efficiently by this production method.
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Informal Comments submitted by applicant in response to the Written Opinion dated Aug. 7, 2007.
Inomiya Kenjin
Ishii Akihiro
Mogi Kaori
Tsuruta Hideyuki
Central Glass Company Limited
Crowell & Moring LLP
Katakam Sudhakar
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