Method for producing multiple emulsions that are stable in...

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S939000, C514S937000, C516S054000, C424S400000, C424S184100, C424S204100, C424S234100

Reexamination Certificate

active

07943154

ABSTRACT:
A process is described for the preparation of storage-stable, multiple emulsions of the water/oil/water (W/O/W) type which comprise one or more active ingredients.The process comprises the stepsa) stirring the active ingredient into an aqueous phase,b) emulsifying the aqueous phase by passing the aqueous phase through a large-pored, porous membrane into an oil phase,c) phase inversion of the emulsion from b), by cooling the mixture at a cooling rate of at least 0.3 K/min, where an emulsifier is added either to the aqueous phase in a) or to the oil phase in b) or to both phases.

REFERENCES:
patent: 6251407 (2001-06-01), Ganne
patent: 6835396 (2004-12-01), Brynjelsen et al.
patent: 2002/0051748 (2002-05-01), Snow et al.
patent: 19630176 (1998-01-01), None
patent: 0481982 (1992-04-01), None
patent: 0489181 (1992-06-01), None
patent: 0564738 (1993-10-01), None
patent: WO 90/00150 (1990-01-01), None
Forster et al. Production of fine disperse and long-term stable oil-in-water emulsion by the phase inversion temperature method. Journal of Dispersion Science and Technology, 1992, vol. 13, No. 2, 183-193.
Higashi et al. Size of lipid microdroplets effects results of hepatic arterial chemotherapy with an anticancer agent in water-in-oil-in-water emulsion to hepatocelluar carcinoma. The Journal of Pharmacology and Experimental Therapeutics, 1999, vol. 289, No. 2, 816-819.
Joscelyne et al. Membrane emulsification—a literature review. Journal of Membrane Science, 2000, vol. 169, 107-117.
Encyclopedia of Pharmaceutical Technology, vol. 3. James Swarbrick. Informa Healthcare USA, Inc. NY, NY. © 2007, p. 1561.
Hideaki Okochi, et al., Preparation and Evaluation of w/o/w Type Emulsions Containing Vancomycin; Advanced Drug Delivery Reviews, vol. 45 (2000), pp. 5-26.
Terrise, I.; M. Seiller, et al. “Multiple W/O/W emulsions, theoretical study” (1992). Congr. Int. Technol. Pharm., 6th 4: 328-35.
Joscelyne, S.M. and G. Tragardh (2000), “Membrane emulsification—a literature review”. J. Membr. Sci 169 (1): 107-117.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for producing multiple emulsions that are stable in... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing multiple emulsions that are stable in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing multiple emulsions that are stable in... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2703565

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.