Method for producing monolithic chromatography columns

Plastic and nonmetallic article shaping or treating: processes – Pore forming in situ – Composite article making

Reexamination Certificate

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C264S656000, C210S656000

Reexamination Certificate

active

10297992

ABSTRACT:
The invention relates to a process for the production of chromatography columns or capillaries containing sorbents of monolithic mouldings which can remain directly in their gelation mould after production. This is achieved by the process according to the invention, in which the gelation mould is repeatedly filled with the monomer sol.

REFERENCES:
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patent: 5679255 (1997-10-01), Cortes et al.
patent: 6395183 (2002-05-01), Valaskovic et al.
patent: 6758966 (2004-07-01), Myers
patent: WO 9503256 (1995-02-01), None
patent: WO 9859238 (1998-12-01), None
patent: WO 99/50654 (1999-10-01), None
Ishizuka et al, Performance of a Monolithic Silica Column in a Capillary under Presure-Driven and Electrodriven Conditions, Analytical Chemistry vol. 72, No. 6 Mar. 15,200,Published on the web Feb. 10, 2000, pp. 1275-1280.
Ishizuka N et al., “Designing monolithic double-pore silica for high-speed liquid chromatography,” Journal of Chromatography, vol. 797, No. 1-2, pp. 133-137, Feb. 1998.
Tang Q et al., “Column technology for capillary electrochromatography,” TRAC, Trends in Analytical Chemistry, vol. 19, No. 11, pp. 648-663, Nov. 2000.

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