Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...
Reexamination Certificate
2007-07-24
2007-07-24
Wehbé, Anne Marie (Department: 1633)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Animal cell, per se, expressing immunoglobulin, antibody, or...
C435S006120, C435S320100, C435S325000, C435S455000, C435S449000
Reexamination Certificate
active
11324255
ABSTRACT:
An improved method for the production of monoclonal antibodies is disclosed.
REFERENCES:
patent: 4399216 (1983-08-01), Axel et al.
patent: 4634665 (1987-01-01), Axel
patent: 4656134 (1987-04-01), Ringold
patent: 4713339 (1987-12-01), Levinson et al.
patent: 4816387 (1989-03-01), Boss
patent: 4816397 (1989-03-01), Boss et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4956288 (1990-09-01), Barsoum
patent: 5179017 (1993-01-01), Axel
patent: 5545403 (1996-08-01), Page
patent: 5545404 (1996-08-01), Page
patent: 5545405 (1996-08-01), Page
patent: 6331415 (2001-12-01), Cabilly et al.
patent: 6455275 (2002-09-01), Axel
patent: 6475787 (2002-11-01), Wood et al.
patent: 7011974 (2006-03-01), Wood et al.
patent: 2003/0153039 (2003-08-01), Wood
patent: 0481790 (1999-02-01), None
patent: WO 81/02426 (1981-09-01), None
patent: WO 88/08035 (1988-10-01), None
patent: WO 87/04187 (1989-07-01), None
Barsoum et al., “Introduction of stable high-copy-number DNA into Chinese hamster ovary cells by electroporation,”DNA and Cell Biology9: 293-300 (1990).
Beidler et al., “Cloning and high level expression of a chimeric antibody with specificity for human carcinoembryonic antigen,”J. Immunol. 141:4053-60 (1988).
Brennand et al., “Cloned cDNA sequences of the hypoxanthine/guanine phosphoribosyltransferase gene from a mouse neuroblastoma cell line found to have amplified genomic sequences,”Proc. Natl. Acad. Sci. USA79:1950-1954 (1982).
Brinkhous et al., “Purified human factor VIII procoagulant protein: Comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs,”Proc. Natl. Acad. Sci. USA82:8752-8756 (1985).
Dorai et al., “The effect of dihydrofolate reductase-mediated gene amplification of the expression of transfected immunoglobulin genes,”J. Immunol. 139:4232-4241 (1987).
Goding et al., “Cellular basis of the immune system” in “Monoclonal antibodies: Principles and Practice,” Third Edition-Academic Press Limited, London: 29-46 (1996).
Kaufman et al., “Control of translation initiation in mammalian cells,” Genetic Engineering 9:155, J. K. Setlow, ed. (Plenum Publishing Corp.) 1987.
Kaufman et al., “Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells,”Mol and Cell Biol. 9:1233-42 (1989).
Liu et al., “Production of a mouse-human chimeric monoclonal antibody to CD20 with potent Fc-dependent biologic activity,”J. Immunol. 139:3521-3526 (1987).
Page et al., “High level expression of the humanized monoclonal antibody Campath-1H in Chinese hamster ovary cells,”Biotechnology9:64-68 (1991).
Schimke et al., “Gene amplification in cultured animal cells,”Cell37:705-713 (1984).
Toole, et al., “Molecular cloning of a cDNA encoding human antihaemophilic factor,”Nature312:342-347 (1984).
Verweij et al., “Full-length von Willebrand factor (vWF) cDNA encodes a highly positive protein larger than the mature vWF subunit,”EMBO J5:1839-1847 (1986).
Weide et al., “Reconstruction of functionally active antibody directed against creatine kinase from separately expressed heavy and light chains in non-lymphoid cells,”Gene51:21-29 (1982).
Wood et al., “Expression of active human factor VIII from recombinant DNA clones,”Nature312:330-337 (1984).
Wood et al., “High level synthesis of immunoglobulins in Chinese hamster ovary cells,”J. Immunol. 145:3011-3016 (1990).
Kaufman Randal J.
Wood Clive R.
Finnegan Henderson Farabow Garrett & Dunner L.L.P.
Wehbe Anne Marie
Wyeth
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