Method for producing molecular compound

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

Reexamination Certificate

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C428S402200, C568S718000

Reexamination Certificate

active

07655820

ABSTRACT:
A method for producing a molecular compound which comprises mixing and kneading a solid host compound and a solid or liquid guest compound by using a kneader and optionally followed by extruding and granulating, wherein the method further comprises one or more of the steps of holding the product at a temperature which is 50° C. or higher and not higher than the emission temperature for the guest compound, washing the formed molecular compound with a solvent capable of dissolving the guest compound, pulverizing in advance the solid host compound, and adding a poor solvent such as water prior to mixing and kneading. The method allows the production of a molecular compound having improved stability.

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patent: 11-071449 (1999-03-01), None
Melhan, Wu et al, “Analysis of Fat-soluble Compounds of Gouqizl by Gas Chromatography/Mass Spectrometry (GC/MS),”Chinese Journal of Pharmaceutical Analysis, vol. 16(6):387-389.
Chinese Office Action, Application No. 200410129976, dated Jan. 20, 2006.
The Society of Powder Technology,Particle Design Engnieering, First Edition, Pub. Sangyo Toshyo Ltd., Feb. 9, 1999, p. 113.
Notice for Filing Opinion, Korean Patent Application No. 10-2003-7007449.

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