Method for producing microcapsule

Details Method for producing microcapsule Method for producing microcapsule

1988-09-23

1990-09-04

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

264 41, 424461, 424462, 424493, 424497, 514800, 514885, 514963, 6048911, A61K 950, A61K 952, A61K 966, B01J 1302

Patent

active

049542982

ABSTRACT:
Microcapsules are advantageously produced with high take-up of a water-soluble drug by preparing a W/O emulsion composed of a water-soluble drug-containing solution as the inner aqueous phase and a polymer-containing solution as the oil phase, dispersing said emulsion in an aqueous phase and subjecting the resulting W/O/W emulsion to an in-water drying, wherein the viscosity of the W/O emulsion used in preparing the W/O/W emulsion is adjusted to about 150 to about 10,000 centipoises.

REFERENCES:
patent: 3043782 (1962-07-01), Jensen
patent: 3523906 (1970-08-01), Vrancken et al.
patent: 3539465 (1970-11-01), Hiestand et al.
patent: 4384975 (1983-05-01), Fong
patent: 4652441 (1987-03-01), Okada et al.
The Theory and Practice of Industrial Pharmacy, edited by L. Lachman et al., Lea & Febiger, Philadelphia, 1970, pp. 384-391.
European Search Report, European Patent Appln. No. 86300308.

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