Method for producing maytansinol and its derivatives

Details Method for producing maytansinol and its derivatives Method for producing maytansinol and its derivatives

1977-06-29

1979-04-24

Shapiro, Lionel M.

Textiles: fiber preparation

C12D 920

Patent

active

041510429

ABSTRACT:
Maytansinol, maytanacine or maytansinol propionate is (are) produced by cultivating a microorganism belonging to the genus Nocardia and being capable of producing maytansinol, maytanacine or maytansinol propionate, causing the microorganism to accumulate maytansinol, maytanacine or maytansinol propionate and recovering the same.
Those compounds are useful for anti-tumor agents.

REFERENCES:
patent: 3896111 (1975-07-01), Kupchan et al.
Journal American Chemical Society, vol. 94, pp. 1354-1356.
Journal American Chemical Society, vol. 94, pp. 5294-5295.

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