Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1982-11-24
1986-05-13
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
4351723, 435253, 435317, C12P 1322, C12N 1500, C12N 120, C12N 100
Patent
active
045886873
ABSTRACT:
A method for producing L-tryptophan by fermentation in high yields employing a microorganism of the genus Bacillus, which has been constructed by a gene splicing technique by incorporating a recombinant plasmid DNA containing an inserted DNA containing fragment controlling resistance to tryptophan-antagonists into a recipient strain of the genus Bacillus. The incorporated DNA fragment is a mutant of the genus Bacillus which was obtained from resistant to tryptophan-antagonists.
REFERENCES:
patent: 4302544 (1981-11-01), Young et al.
patent: 4363875 (1982-12-01), Akashiba et al.
patent: 4371614 (1983-02-01), Anderson et al.
patent: 4430434 (1984-02-01), Sanders et al.
Chemical Abstracts, vol. 95, p. 339, (1981), Abstract No. 57898q: Okunev, O. V. et al, "Obtaining Hybrid Plasmids Containing Bacillus subtilis Genes".
Keggins et al, Proc. Natl. Acad. Sci., vol. 75, No. 3, pp. 1423-1427 (1978), "Molecular Cloning of Genetically Active Fragments of Bacillus DNA in Bacillus subtilis and Properties of the Vector Plasmid pUB110".
Methods in Enzymology, vol. 68, Recombinant DNA; Wu, R. ed., Academic Press, New York, pp. 342-357 (1979).
Enei Hitoshi
Kawashima Hiroki
Kurahashi Osamu
Nakamori Shigeru
Tsuchida Takayasu
Ajinomoto Company Incorporated
Teskin Robin Lyn
Wiseman Thomas G.
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