Method for producing L-phenylalanine by fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435 68, 435 70, 435 91, 4351723, 435253, 435839, 435317, 536 27, 935 29, 935 60, 935 74, C12P 1322, C12P 2100, C12P 2102, C12P 1934, C12N 1500, C12N 120, C12N 100, C12R 1125, C07H 2104

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045915628

ABSTRACT:
A method for producing L-phenylalanine by fermentation which comprises aerobically culturing an L-phenylalanine-producing microorganism in an aqueous culture medium and recovering the L-phenylalanine accumulated in the culture medium, the L-phenylalanine-producing microorganism having been constructed by incorporating a recombinant plasmid DNA, into which a DNA fragment controlling resistance to a phenylalanine antagoinst, obtained from a chromosomal DNA of a mutant of the genus Bacillus resistant to the phenylalanine antagonist, has been inserted, into a recipient strain of the genus Bacillus.

REFERENCES:
patent: 4407952 (1983-10-01), Tsuchida et al.
Williams et al: in Molecular Cloning and Gene Regulation in Bacilli, Ganesan et al (Ed.), Academic Press, New York, 1982, pp. 91-95.
Yoneda: in Molecular Cloning and Gene Regulation in Bacilli, Ganesan et al (Ed.), Academic Press, New York, 1982, pp. 111-120.
Kreft et al: in Molecular Cloning and Gene Regulation in Bacilli, Ganesan et al (Ed.), Academic Press, New York, 1982, pp. 145-157.

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