Method for producing L-phenylalanine by fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435172, 435849, 435317, C12N 1500, C12P 1322, C12R 119

Patent

active

044079524

ABSTRACT:
L-phenylalanine is produced by fermentation by culturing in a culture medium an L-phenylalanine producing microorganism constructed by incorporating a hybrid plasmid in a recipient strain of the genus Escherichia and recovering the L-phenylalanine which accumulates in the culture medium, said hybrid plasmid containing a deoxyribonucleic acid fragment possessing genetic information related to L-phenylalanine production and obtained from a phenylalanine analogue resistant mutant of the genus Escherichia.

REFERENCES:
patent: 3660235 (1972-05-01), Okumura et al.
patent: 3759790 (1973-09-01), Nakayama et al.
patent: 3909353 (1975-09-01), Tsuchida et al.
patent: 3917511 (1975-11-01), Nakayama et al.
patent: 4237224 (1980-12-01), Cohen et al.
patent: 4278765 (1981-07-01), Debabov et al.

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