Method for producing L-lysine

Details Method for producing L-lysine Method for producing L-lysine

1997-12-05

1999-12-21

Degen, Nancy

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

435 691, 435106, 4352523, 43525232, 4353201, 536 231, C12P 100, C12P 2102, C12N 1563, C07H 2104

Patent

active

060047739

ABSTRACT:
A coryneform bacterium harboring an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, and comprising an enhanced DNA sequence coding for a dihydrodipicolinate reductase, an enhanced DNA sequence coding for dihydropicolinate reductase, an enhance DNA sequence coding for dihydropicolinate synthase, an enhanced DNA sequence coding for diaminopimelate decarboxylase and an enhanced DNA sequence coding for aspartate aminotransferase; a method for producing L-lysine comprising the steps of cultivating the coryneform bacterium in an appropriate medium to allow L-lysine to be produced and accumulated in a culture of the bacterium, and collecting L-lysine from the culture; and a recombinant DNA usable for production of the coryneform bacterium.

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PHSG299 TaKARa catalog.
ATCC No.: 13869 Organism: Corynebacterium glutamic.

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