Method for producing L-leucine

Details Method for producing L-leucine Method for producing L-leucine

2007-05-22

2007-05-22

Ramirez, Delia M. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S252300, C435S320100, C435S069100, C435S193000, C435S015000, C435S116000, C435S440000, C435S115000, C530S350000, C536S023100, C536S023200

Reexamination Certificate

active

10601634

ABSTRACT:
There is provided a method for producing L-leucine using bacterium belonging to the genusEscherichia, which produces L-valine, L-isoleucine and L-homoleucine in an amount of less than 1% of that of L-leucine produced due to inactivation of ilvE gene coding for branched chain amino acid transaminase and produces increased amount of L-leucine due to increasing the activity of the aromatic amino acid transaminase encoded by tyrB gene.

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