Method for producing L-isoleucine with a fermentation process

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435115, 435106, 4352528, 435849, C12P 1306, C12P 1308, C12N 120, C12N 100

Patent

active

056959729

ABSTRACT:
The present invention provide a method for the industrial production of L-isoleucine which is useful as pharmaceuticals, foods, feed additives and the like. The method comprises cultivating in a nutrient medium a microorganism belonging to the genus Escherichia which is capable of rapidly growing in a medium containing L-homoserine as the single nitrogen source and has an ability to produce L-isoleucine in the medium, producing and accumulate L-isoleucine in a culture and recovering L-isoleucine therefrom.

REFERENCES:
patent: 4411991 (1983-10-01), Hirakawa et al.
patent: 5474918 (1995-12-01), Kino et al.
Brock. Biology of Microorganisms, 3rd Ed, p. 355, 1979.
Herrmann and Somerville. Amino Acids-Biosynthesis and Genetic Regulation. 1983, pp. 148 and 246.

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