Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1982-12-10
1985-03-12
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
4351723, 435839, C12P 1324, C12N 1500, C12R 1125
Patent
active
045045810
ABSTRACT:
L-Histidine producing microorganisms which have been constructed by introducing a recombinant plasmid DNA inserted on a chromosomal DNA fragment into a recipient strain of the genus Bacillus. These microorganisms are employed to produce L-histidine in higher than normal yields. The recombinant plasmid DNA inserted is obtained from a donor mutant strain of Bacillus subtilis which is resistant to certain L-histidine antagonists. The resistant plasmid confers the properties of the mutant strain upon the recipient Bacillus subtilis to make its high yield of product even higher.
REFERENCES:
patent: 3902966 (1975-09-01), Chibata et al.
patent: 4388405 (1983-06-01), Sano et al.
Enei Hitoshi
Kawashima Hiroki
Kurahashi Osamu
Nakamori Shigeru
Tsuchida Takayasu
Ajinomoto Company Incorporated
Shapiro Lionel M.
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