Method for producing L-aspartic acid

Details Method for producing L-aspartic acid Method for producing L-aspartic acid

1984-05-30

1987-09-08

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

4351723, 435253, 435317, 935 60, 935 73, C12P 1320, C12N 1500, C12N 120, C12N 100

Patent

active

046924094

ABSTRACT:
A novel microorganism of the genus Escherichia containing a hybrid plasmid prepared by integrating a plasmid with a deoxyribonucleic acid carrying the gene for aspartase which is obtained from a microorganism of the genus Escherichia. An industrially advantageous method for producing L-aspartic acid comprising contacting a culture of the novel microorganism, microbial cells collected from the culture or a processed material of the microbial cells with fumaric acid and ammonia to produce L-aspartic acid and then collecting L-aspartic acid thus produced is also disclosed.

REFERENCES:
patent: 4326029 (1982-04-01), Yukawa et al.
patent: 4430430 (1984-02-01), Momose et al.
Komatsubara, S. et al., J. Biotechnology, vol. 3, pp. 281-291, 1986.
Guest, J. et al., J. of Gen. Microbiol., vol. 130, pp. 1271-1278, May, 1984.
Spencer, M. et al., J. of Gen. Microbiol., vol. 97, pp. 73-82, 1976.
Takagi, J. et al., Nuc. Acids Res., vol. 13, No. 6, pp. 2063-2074, 1985.

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