Method for producing L-amino acid using methylotroph

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S193000, C435S320100, C435S252000, C435S006120, C536S023100

Reexamination Certificate

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07439038

ABSTRACT:
A DNA encoding for a mutant of LysE protein, or a homologous protein thereof, of a coryneform bacterium, wherein the mutant, when introduced into a methanol-assimilating bacterium imparts resistance to L-lysine analogue. The DNA encoding for a mutant of LysE protein, or a homologous protein thereof, is introduced into a methanol-assimilating bacterium to improve L-lysine and L-arginine productivity of the methanol-assimilating bacterium.

REFERENCES:
patent: 3907637 (1975-09-01), Nakayama et al.
patent: 3907641 (1975-09-01), Nakayama et al.
patent: 5217883 (1993-06-01), Anazawa et al.
patent: 5972663 (1999-10-01), Winterhalter et al.
patent: 6303381 (2001-10-01), Gunji et al.
patent: 2003/0049804 (2003-03-01), Pompejus et al.
patent: 2003/0049805 (2003-03-01), Nagase et al.
patent: 2003/0113899 (2003-06-01), Yamaguchi et al.
patent: 2003/0124687 (2003-07-01), Gunji et al.
patent: 724536 (1997-07-01), None
patent: 1016710 (2000-07-01), None
patent: 1108790 (2001-06-01), None
patent: 1188822 (2002-03-01), None
patent: 1 266 966 (2002-12-01), None
patent: 45-25273 (1970-08-01), None
patent: 50-25790 (1975-03-01), None
patent: 52-18886 (1977-02-01), None
patent: WO90/12105 (1990-10-01), None
patent: WO 0100843 (2001-01-01), None
Brown, T., Hybridization Analysis of DNA Blots, 1993, Current Protocols in Molecular Biology, Chapter 5. p. 2.10.1.
U.S. Appl. No. 10/716,470, filed Nov. 20, 2003, Gunji et al.
U.S. Appl. No. 10/716,473, filed Nov. 20, 2003, Gunji et al.
Marina Vrljic et al., A new type of transporter with a new type of cellular function: L-lysine export fromCorynebacterium glutamicum, Molecular Microbiology, 1996, p. 815-826, vol. 22, No. 5.
H. Motoyama et al., Effects of the amplification of the genes coding for the L-threonine biosynthesis enzymes on the L-threonine production from methanol by a gram-negative obligate methylotroph,Methylobacillus glycogens, Appl. Microbiol. Biotechnol., 1994, p. 67-72, vol. 42.
L. V. Kletsova et al., Mutants of the obligate methylothrophMethylobacillus flagellatumKT defective in genes of the ribulose monophosphate cycle of formaldehyde fixation, Arch. Microbiol., 1988, p. 441-446, vol. 149.
Neil R. Wyborn et al., Molecular characterization of formamidase fromMethylophilus methylotrophus, Eur. J. Biochem., 1996, p. 314-322, vol. 240.
Owen Jenkins et al.,Methylophilus: a New Genus of Methanol-Utilizing Bacteria, International Journal of Systematic Bacteriology, Oct. 1987, p. 446-448, vol. 37, No. 4.
Teizi Urakami et al., Emendation ofMethylobacillus: Yordy and Weaver 1977, a Genus for Methanol-Utilizing Bacteria, International Journal of Systematic Bacteriology, Oct. 1986, p. 502-511, vol. 36, No. 4.
Gunji, Y., et al., “Enhancement of L-lysine production in methylotrophMethylophilus methylotrophusby introducing a mutant LysE exporter,” J. Biotechnol. 2006;127:1-13.
Motoyama, H., et al., “Amino Acid Production from Methanol byMethylbacillus glycogensMutants: Isolation of L-Glutamic Acid Hyper-producing Mutants fromM. glycogensStrains, and Derivation of L-Threonine and L-Lysine-producing Mutants from Them,” Biosci. Biotech. Biochem. 1993;57(1):82-87.
Motoyama, H., et al., “Overproduction of L-Lysine from Methanol byMethylobacillus glycogensDerivatives Carrying a Plasmid with a MutateddapAGene,” Appl. Environmen. Microbiol. 2001;67(7):3064-3070.
French Patent App. No. 0313574 (Jun. 5, 2007), Search Report.

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