Method for producing L-3, 4-dihydroxyphenyalanine by Erwinia hav

Details Method for producing L-3, 4-dihydroxyphenyalanine by Erwinia hav Method for producing L-3, 4-dihydroxyphenyalanine by Erwinia hav

1993-03-24

1994-08-16

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435232, 435847, 4352521, C12P 1322

Patent

active

053386728

ABSTRACT:
The present invention relates to improved methods for producing L-3, 4-dihydroxyphenylalanine from catechol, pyruvic acid and ammonium ion, or catechol and L-serine, by utilizing .beta.-tyrosinase activity of a microorganism which belongs to the genus Erwinia. According to the method of the present invention, L-3,4-dihydroxyphenylalanine can be produced at a lower cost and higher efficiency as compared with that in the conventional method.

REFERENCES:
patent: 3791924 (1974-02-01), Ogata et al.
Database WPIL, AN-93-199733, JP-A-5 123 177, May 21, 1993.
Database WPIL, AN-76-31196X, JP-B-51 009 394, Mar. 27, 1976.
Argicultural and Biological Chemistry, vol. 37, No. 3, 1973, pp. 493-499, H. Enei, et al., "Synthesis of L-Tyrosine or 3,4-Dihydroxyphenyl-L-Alanine From DL-Serine And Phenol Or Pyrocathechol".
Enei, H. et al., "Distribution of Tyrosine Phenol Lyase in Microorganisms", Agr. Biol. Chem., vol. 36, No. 11, pp. 1861-1868, 1972.
Soda, K. et al., "Amino Acids", In. Biotechnology, vol. 3, Dellweg, H. (ed.); Publishi: Verlag Chemie: pp. 503-506, 1983.

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