Method for producing interferons

Details Method for producing interferons Method for producing interferons

1984-11-26

1987-04-07

Hazel, Blondel

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

424 85, C12P 2100

Patent

active

046561315

ABSTRACT:
A method for producing high yields of interferons which comprises cultivating a microorganism carrying an expression vector with a structural gene of interferon inserted therein in a chemically defined medium containing L-glutamic acid and an iron ion source and preferably further containing an zinc ion source or zinc and copper ion sources, and recovering interferon from the culture.

REFERENCES:
patent: 4518584 (1985-05-01), Mark et al.
Goeddel et al., Nature, vol. 287, pp. 411-416, 1980.

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