Method for producing implantable ligament and tendon prostheses

Details Method for producing implantable ligament and tendon prostheses Method for producing implantable ligament and tendon prostheses

1987-06-15

1988-09-20

Lieberman, Paul

Bleaching and dyeing; fluid treatment and chemical modification

Treatment of hides, skins, feathers and animal tissues

Internal tissues

623 1, 623 2, A61L 1700

Patent

active

047722886

ABSTRACT:
A method of making implantable ligament and tendon prostheses from natural collagen-containing tissues is described. The tissues used are those wherein the collagen fibers are aligned in one direction such as in ligaments or tendons. The method comprises disrupting the interfibrillar matrix physically by mechanical means such as a roller or rollers in order to generate an expanded network of fibers that are more easily further treated chemically and which also generate a more favorable substrate for tissue ingrowth after implantation. Prostheses made from separated collagen fiber bundles which retain their natural configuration and length (as opposed to reconstituted collagen), exhibit improved softness and flexibility when compared with prostheses made from conventional chemically fixed (e.g., glutaraldehyde cross-linked) tendons which have not been separated as described herein. Another implementation of the developed new technology allows for the formation of composites between the dissociated collagen fibers involving two or more tissues or between collagen and synthetic fibers. These composites can also include absorbable materials.

REFERENCES:
patent: 2640752 (1953-06-01), Davis et al.
patent: 3114593 (1963-12-01), Griset et al.
patent: 3304557 (1967-02-01), Polansky
patent: 3526228 (1970-09-01), Lyng
patent: 3551560 (1970-12-01), Thiele
patent: 4378224 (1983-03-01), Nimni et al.
patent: 4383832 (1983-05-01), Fraefel et al.
patent: 4481009 (1984-11-01), Nashef

Affiliated with

Also associated with

Rating

Method for producing implantable ligament and tendon prostheses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing implantable ligament and tendon prostheses , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing implantable ligament and tendon prostheses will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1746307