Method for producing human insulin-like growth factor I

Details Method for producing human insulin-like growth factor I Method for producing human insulin-like growth factor I

2008-04-30

2011-10-18

Stoica, Elly-Gerald (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S303000, C424S245100, C435S252330

Reexamination Certificate

active

08039434

ABSTRACT:
A method is provided for producing hIGF-I with high purity and yield. This is a method for producing human insulin-like growth factor I, having a step of removing modified human insulin-like growth factor I from the human insulin-like growth factor I, the step including:(A) a step of adjusting the pH of a culture liquid of a human insulin-like growth factor I producing bacteria to 8 or more after completion of culture;(B) a step of letting the culture liquid obtained in step (A) stand; and(C) a step of removing the producing bacteria from the culture liquid obtained in step (B).

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