Method for producing human antibody

Details Method for producing human antibody Method for producing human antibody

1985-07-01

1989-05-23

Tarcza, John E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

4351722, 43524027, 435948, 935100, C12P 2100, C12N 500, C12N 1500, C12R 191

Patent

active

048330779

ABSTRACT:
A method of effectively producing antobodies by creating antibody-producing hybrid cell lines utilizing an established B cell line as a parent cell lines and fusing these B cells to normal, human antibody-producing cells. A preferred established B cell line for use in this invention consists of B cells characterized by the presence of immunoglobulin at their cell surface.

REFERENCES:
patent: 4271145 (1981-06-01), Wands et al.
Steinitz et al., Nature 269, pp. 420-422, (1977).
Huang et al., Journal of the National Cancer Institute, 43(5), pp. 1119-1128, (1969).

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