Method for producing high dielectric strength microvalves

Coating processes – Direct application of electrical – magnetic – wave – or... – Polymerization of coating utilizing direct application of...

Reexamination Certificate

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C427S554000, C427S235000

Reexamination Certificate

active

07022381

ABSTRACT:
A microvalve having a cast-in-place and lithographically shaped mobile, polymer monolith for fluid flow control in microfluidic devices and method of manufacture. The microvalve contains a porous fluorinated polymer monolithic element whose pores are filled with an electrically insulating, high dielectric strength fluid, typically a perfluorinated liquid. This combination provides a microvalve that combines high dielectric strength with extremely low electrical conductivity. These microvalves have been shown to have resistivities of at least 100 GΩ and are compatible with solvents such as water at a pH between 2.7 and 9.0, 1-1 propanol, acetonitrile, and acetone.

REFERENCES:
Hasselbrink, Jr., et al., “High Pressure Microfluidic Control in Lab-on-a-Chip Devices Using Mobile Polymer Monoliths,” Anal. Chem. 2002, 74, 4913-4918.
Kirby et al., “Voltage-addressable on/off microvalves for high-pressure microchip separations,” Journal of Chromatography A, 979 (2002) 147-154.

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