Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1993-12-13
1999-10-12
Reeves, Julie
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 435328, 5303871, 5303873, 4241331, 4241341, A61K 39395, C07K 1600, C07K 1646, C12N 1513
Patent
active
059654058
ABSTRACT:
Methods for preparing Fv fragments which lack linking polypeptides in eukaryotic cells are provided.
REFERENCES:
patent: 4642334 (1987-02-01), Moore et al.
patent: 4853871 (1989-08-01), Pantoliano et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 5091513 (1992-02-01), Huston et al.
Nakaki et al., "Enhanced Transcription of the 78,000-Dalton Glucose-Regulated Protein (GRP78) Gene and Association of GRP78 with Immunoglobulin Light Chains in a Nonsecreting B-Cell Myeloma Line (NS-1)", Molecular and Cellular Biology, vol. 9, No. 5, May 1989, pp. 2233-2238.
Chang et al., "Glucose -Regulated Protein (GRP94 and GRP78) Genes Share Common Regulatory Domains and Are Coordinately Regulated by Common trans-Acting Factors", Molecular and Cellular Biology, vol. 9, No. 5, May 1989, pp. 2153-2162.
Ting et al., "The nucleotide sequence encoding the hamster 78-kDa glucose-regulated protein (GRP78) and its conservation between hamster and rat", Gene, 55 (1987) pp. 147-152.
Whittle et al., "Expression in COS cells of a mouse-human chimaeric B72.3 antibody", Protein Engineering, vol. 1, No. 6, pp. 499-505, 1987.
Hendershot, L. et al.; "The Role of immunoglobulin Heavy Chain Binding Protein . . . "; Immunology Today, vol. 8, No. 4, pp. 111-114, 1987.
Gething, M. et al.; "Expression of Wild-Type And Mutant Forms Of Influenza Hemagglutinin . . . "; Cell; vol. 46, pp. 939-950, Sep. 12, 1986.
Verhoyen et al., Bio. Essays 8(2): 74-78 (1988).
Morrison et al. Science vol. 229:1202 1985.
Wood et al. Nature vol. 374:446, 1985.
Rudikoff et al. PNAS. vol. 83 p. 7875 1986.
Bodmer Mark William
Owens Raymond John
Riechmann Lutz
Winter Gregory Paul
Yarranton Geoffrey Thomas
Celltech Limited
Reeves Julie
Schneller John W.
LandOfFree
Method for producing Fv fragments in eukaryotic cells does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for producing Fv fragments in eukaryotic cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing Fv fragments in eukaryotic cells will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-651352