Method for producing factor VIII:C-type proteins

Details Method for producing factor VIII:C-type proteins Method for producing factor VIII:C-type proteins

1992-01-17

1993-10-05

Low, Christopher S. F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 691, 4351723, 4353201, 4352402, 4352403, 43524031, 930100, 935 33, 935 34, 935 60, 935 70, C12P 2100, C12N 502

Patent

active

052504212

ABSTRACT:
An improved method for producing Factor VIII:c-type proteins is disclosed which involves culturing mammalian cells which are capable of expressing the protein. In accordance with this invention the cells are cultured in a medium containing an effective amount of a substance comprising (a) von Willebrand Factor-type protein, (b) a phospholipid or phospholipid mixture, or a mixture of (a) and (b).

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