Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Bacteria or actinomycetales
Patent
1997-04-07
1999-11-02
Naff, David M.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Bacteria or actinomycetales
4242821, 435 29, 435 30, 435 34, 435 38, 435822, 435 71, 4352521, A01N 6300, A61K 4500, C12N 112, C12Q 104
Patent
active
059765259
ABSTRACT:
Methods using in vitro processes are disclosed for inducing or enhancing expression of enteric bacterial antigens or virulence factors. The methods, therefore, produce antigenically enhanced enteric bacteria. Also disclosed are methods for using the antigenically enhanced bacteria, as well as vaccines containing the enteric bacteria. Specifically, a whole enteric bacteria or components thereof are provided by Campylobacter species. In addition to this species there are other enteric bacteria, such as Yersinia spp., Bacteroides spp., Klebsiella spp., Gastrospirillum spp., Enterobacter spp., Salmonella spp., Aeromonas spp., Vibrio spp., Clostridium spp., Enterococcus spp., and Escherichia coli, which are useful for inducing or enhancing expression of enteric bacterial antigens and/or virulence factors.
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Frey Steven Michael
Pace John Lee
Walker Richard Ives
Antex Biologics Inc.
Naff David M.
Ware Deborah
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