Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Reexamination Certificate
2006-10-03
2006-10-03
Lilling, Herbert J. (Department: 1651)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
C435S252330, C435S823000, C435S849000
Reexamination Certificate
active
07115389
ABSTRACT:
A method for producing a dipeptide including the step of exposing a carboxy component and an amine component to an enzyme having an activity to hydrolyze amino acid ester. Such a hydrolase has been found among enzymes in bacteria. The method is useful for producing a peptide simply and inexpensively with a high yield without taking complicate synthetic methods.
REFERENCES:
patent: 2005/0037453 (2005-02-01), Tonouchi et al.
patent: 0 278 787 (1988-08-01), None
patent: 0 359 399 (1990-03-01), None
patent: 53-92729 (1978-08-01), None
patent: 1-96194 (1989-04-01), None
patent: 6-234715 (1994-08-01), None
patent: WO 90/01555 (1990-02-01), None
patent: WO 04/022733 (2004-03-01), None
patent: PCT/JP2004/010990 (2005-02-01), None
patent: WO 05/010196 (2005-02-01), None
S.Akabori, et al., “Protection of Amide-Nitrogen for Peptide Synthesis. A Novel Synthesis of Peptides Containing C-Terminal Glutamine”, Bull. Chem. Soc. Jpn, May 1961, p. 739.
Y. Shimonishi, et al., “Studies on the Synthesis of Peptides Containing Glutamine as the C-Terminal. I. Protection of Amide-Nitrogen With Xanthyl Group During Peptide Synthesis”, Bull. Chem. Soc. Jpn., vol. 35, No. 12, Dec. 1962, pp. 1966-1970.
Y. Shimonishi, “Studies of the Synthesis of Peptides Containing C-Terminal Glutamine. II. The Synthesis and use of Alpha-Para-Nitrobenzyl Gamma-Methyl L-Glutamate”, Bull. Chem. Soc. Jpn., vol. 37, No. 2, Feb. 1964, pp. 200-203.
K.Morihara, et al., “Alpha-Chymotrypsin as the Catalyst for Peptide Synthesis”, Biochem. J., (1977), 163, pp. 531-542.
H. Meos, et al., “Single-Step Synthesis of Kyotorphin in Frozen Solutions by Chymotrypsin”, Tetrahedron: Asymmetry, vol. 4, No. 7, pp. 1559-1564, 1993, XP-002981749.
V. Tougu, et al., “Peptide Synthesis by Chymotrypsin in Frozen Solutions”, FEBS Letters, vol. 329, No. 1-2, pp. 40-42, Aug. 1993, XP-002981750.
J.J. Polderman-Tijmes, et al., “Cloning, Sequence Analysis, and Expression inEscherichia coliof the Gene Encoding an Alpha-Amino Acid Ester Hydrolase From Acetobacter Turbidans”, Applied and Environmental Microbiology, vol. 68, No. 1, pp. 211-218, Jan. 2002, XP-001121414.
Hara Seiichi
Yokozeki Kenzo
Ajinomoto Co. Inc.
Lilling Herbert J.
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