Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1993-03-05
1995-06-06
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
4352551, 4352541, 435911, 435938, 435921, 435944, C12P 1306, C12N 116
Patent
active
054222559
ABSTRACT:
A high concentration of DL-alanine can be supplied in a culture medium and D-alanine can be efficiently obtained with high yield for a short time by cultivating a yeast which belongs to the genus Candida, the genus Cryptococcus, the genus Hansenura or the genus Trichosporon and has an ability to assimilate L-alanine and not to assimilate substantially D-alanine in a culture medium containing substantially DL-alanine as a single carbon source and a single nitrogen source under an acidic condition. Moreover, because very little other organic by-product and organic impurity exists in the culture medium when the cultivation is completed, it becomes easy to separate and refine the D-alanine.
REFERENCES:
patent: 4783404 (1988-11-01), Aretz et al.
ATCC Catalogue of Fungi, 1987 p. 73.
ATCC Catalog of Fungi, 1987, 17th ed, pp. 123, 184, 290, 381.
Chemical Abstracts, vol. 67 1967 #9 42581d "Preparation of optically active alanine from DL-alanine by yeast" Oshima et al. Hakko to Taisha No. 15 89-94 discussion 94 (1967) (Japan).
Imamura Shinzo
Ito Noriko
Sato Haruyo
Marx Irene
Miller Austin R.
Toray Industries Inc.
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