Method for producing cytosine nucleoside compounds

Details Method for producing cytosine nucleoside compounds Method for producing cytosine nucleoside compounds

2005-02-22

2005-02-22

Wilson, James O (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S022100, C536S026100, C536S026800, C435S087000, C435S089000

Reexamination Certificate

active

06858721

ABSTRACT:
The invention provides a method for producing a cytosine nucleoside compound from pentose-1-phosphate and cytosine or a derivative thereof using a nucleoside phosphorylase reactive to cytosine or a bacterium having the enzyme activity. The invention also provides a method for specifically reducing an activity to degrade the substrates or the product, resulting in efficient production of the cytosine nucleoside compound. According to the invention, little by-product is produced in producing cytonucleocide compounds.

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