Method for producing capsular polysaccharides

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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C12P 1904

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053309030

ABSTRACT:
Structurally altered capsular polysaccharides are produced by mutant bacteria. These polysaccharides are isolated by selecting a wild type bacterial strain and a phage producing degradative enzymes that have substrate specificity for the capsular polysaccharides produced by the wild type bacteria. Phage-resistant mutants producing capsular polysaccharides are selected and the structurally altered capsular polysaccharide is isolated therefrom.

REFERENCES:
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"Turbulent-Flow Properties of Polysaccharide Solutions" By J. W. Hoyt, 1968, pp. 207-215.
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"Drag Reduction in Polysaccharide Solutions" By: J. W. Hoyt, 1985, pp. 17-21.
"Yeasts Producing Exopolysaccharides with Drag-Reducing Activity" By G. R. Petersen, et al. 1990, pp. 255-259.
"Rheologically Interesting Polysaccharides From Yeasts" By Gene R. Petersen, et al. 1989 pp. 845-867.
"Structural Modification of Polysaccharides, A Biochemical-Genetic Approach" By: Roger G. Kern and Gene R. Petersen, Dec. 1991 pp. 73-78.
"Experiments in Molecular Genetics" By Jeffrey H. Miller, 1972, pp. 121-129.

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