Method for producing biologically active polysaccharide RON subs

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435183, 4352521, 435822, 536 111, 536 551, 536127, 53612312, C12N 120, C12P 1904

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active

053326679

ABSTRACT:
A biologically active polysaccharide RON substance which is excellent in such biological activities as antitumor activities, is produced by using a microorganism belonging to the genus Leuconostoc, which has an activity of producing the RON substance.

REFERENCES:
patent: 4762825 (1988-08-01), Takeo et al.
Gherna et al., ATCC Catalogue of Bacteria & Bacteriophages, 17th edition, 1989, p. 123, American Type Culture Collection.
Marina E. Preobrazhenskaya et al, Studies on Some Biologically Active Dextrans, Carbohydrate Research, 66(1978) pp. 213-223.
S. M. Navashin et al, Antitumor and Antibacterial Activity of Dextran LU-122 and Its Effect on Macrophage Activity, Curr. Chemother. Immunother., Proc. Int. Congr. Chemther, 12th, 1, pp. 190-192 (1982).
Chemical Abstracts, Jan. 2, 1989, vol. 110, 387w, Suguru et al, "Studies of an antitumor Polysaccaride RBS derived from rice bran. II Preparation and general properties of RON, an active fraction of RBS." & Chem. Pharm. Bull. 1988.
Chemical Abstracts, Oct. 29, 1973, vol.79:10174n, OLLE, "Structural studies on the extracellular polysaccharides elatorated by Leoconostoc Mesenteroides NRRL B-512 and Diplococcus pneumoniae Type II" & Chem. Commun. Univ. Stockholm 1973.
Sneath et al. "Bergey's Manual of Systematic Bateriology", 1986, vol. 2. pp. 1071-1075.

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