Method for producing antibodies which catalyze chemical reaction

Details Method for producing antibodies which catalyze chemical reaction Method for producing antibodies which catalyze chemical reaction

1989-09-22

1991-08-06

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

435193, 435196, 4351722, 424 858, 530387, C12N 900, C12N 1502, A61K 39395

Patent

active

050377507

ABSTRACT:
A method for increasing the rate of chemical reactions involving the conversion of at least one reactant to at least one product involves contacting the reactant with an appropriate monoclonal antibody under conditions permitting the formation of a complex between the antibody and the reactant. The complexed reactant is converted to the product which is then released from the complex. The monoclonal antibody may employ a cofactor and may be directed to a known substrate of an enzyme. Methods for preparing such monoclonal antibodies are also disclosed.

REFERENCES:
patent: 4888281 (1989-12-01), Schochekman et al.

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