Method for producing antibodies in plant cells

Details Method for producing antibodies in plant cells Method for producing antibodies in plant cells

1994-07-25

2000-06-27

Smith, Lynette R. F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

4351723, 435419, 435468, 435 691, 435 698, 435 701, 435 7021, 536 235, 536 241, C12N 1529, C12N 1582, C12N 1500, A01H 400

Patent

active

060805609

ABSTRACT:
A method for producing antibodies in plant cells including the steps of providing a genetic construct that encodes a secretable mammalian single chain antibody, delivering copies of the construct into a liquid suspension culture of tobacco cells, selecting for cells that have acquired the genetic construct, allowing the antibody to accumulate in the liquid to a concentration over 25 mg/l and isolating the antibody away from the tobacco cells.

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