Method for producing an in vivo environment suitable for human e

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

6048901, 514170, 514899, 514967, 424431, 424432, 600 34, 600 33, A61K 900, A61K 3156

Patent

active

048162574

ABSTRACT:
A method for producing, in a functionally agonadal human female body, an environment suitable for the implantation, nutrition, and development of an embryo, comprising the placement of at least one carrier containing at least one releasable steroid hormone into the vagina of the human female.

REFERENCES:
patent: 3545439 (1970-12-01), Duncan
patent: 3656483 (1972-04-01), Rudel
patent: 3755575 (1973-08-01), Lerner
patent: 3845761 (1974-11-01), Zaffaroni
patent: 3896819 (1975-07-01), Zaffaroni
patent: 3957982 (1976-05-01), Lachnit-Fixson et al.
patent: 4071623 (1978-01-01), Van der Vies
patent: 4091028 (1981-09-01), Vorys
patent: 4323548 (1982-04-01), Scherm
patent: 4425339 (1984-01-01), Pitchford
patent: 4439432 (1984-03-01), Peat
patent: 4551148 (1985-11-01), Riley et al.
Lutjen, P., et al, "The Establishment and Maintenance of Pregnancy Using In itro Fertilization and Embryo Donation in a Patent with Primary Ovarian Failure," Nature, 307, 174 (1984).
Bustillo, M. et al., "Nonsurgical Ovum Transfer as a Treatment in Infertile Women: Preliminary Experience," J. Amer. Med. Assoc. vol. 251, No. 9, 1171 (1984).
Hodgen, G. D., "Surrogate Embryo Transfer Combined with Estrogen-Progesterone Therapy in Monkeys," J. Amer. Med. Assoc., 250, 2167 (1983).
Folkman, J., et al, "The Use of Silicone Rubber as a Carrier for Prolonged Drug Therapy", J. Surg. Res., 4, 139 (1964).
Kind, F. A., et al, "Sustained Release Hormonal Preparations," Acta Endrocinol. Suppl. (Copenh.), 151, 55:5 (1971).
Hunter, D. J. S., et al, "Plasma Levels of Estrogen, Luteinizing Hormone and Follicle Stimulating Hormone Following Castration and Estradiol Implant," Obstet. Gynecol., 49, 180 (1977).
Loeper, J., et al, "The Influence of Estrogen Therapy on Triglycerides: Importance of the Choice of Substance and Route of Administration," Nouv. Presse Med. 6, 2747 (1977).
Whitehead, M. I., et al, "Adsorption and Metabilism of Oral Progesterone," Br. Med. J., 280, 825 (1980).
Nillius, S. J., et al, "Plasma Levels of Progesterone After Vaginal, Rectal or Instramuscular Administration of Progesterone," Am. J. Obstet. Gynecol., 110, 470 (1971).
Katz, Z., et al, "Teratogenicity of Progestogens Given During the First Trimester of Pregnancy," Obstet. Gynecol. 65, 775 (1983).
Resseguie, L. J., et al, "Congenital Malformations Among Offspring Exposed in Utero to Progestins, Olmsted County, Minnesota, 1936-1974," Fertil. Steril., 43, 514 (1985).
Mishell, D. R., "Absorption of Steroids ThroughSilastic in Animals and Humans-Results of Studies in Humans," Advances in Planned Parenthood, 5, 151 (1970).
Sivin, I., et al, "A Multicenter Study of Levonorgestrel-estradiol Contraceptive Vaginal Rings. I. Use Effectiveness. An International Comparative Trial," Contraception, 24, 341 (1981).
Mishell, D. R. et al, "Clinical Performances and Endocrine Profiles with Contraceptive Vaginal Rings Containing a Combination of Estradiol and D-Norgestrel," Am. J. Obstet. Gynecol., 130, 55 (1978).
Toivonen, J., "Pituitary and Gonadal Function During the use of Progesterone-or Progesterone-estradiol-releasing Vaginal Rings," Int. J. Fertil, 25, 106 (1980).
Mishell, D. R. et al, "Inhibition of Ovulation With Cyclic Use of Progesten-Impregnated Intravaginal Devices," Am. J. Obstet. Gynecol., 113 927 (1972).
Johansson, E. D. B. et al, "The Effect of Progestin R2323 Released From Vaginal Rings on Ovarian Function," Contraception, 12 299 (1975).
Mishell, D. R. et al, "Contraception By Means of a Silastic Vaginal Ring Impregnated With Medroxyprogesterone Acetate," Contraception 107, 100 (1970).
Mishell, D. R., et al, "Contraceptive Effect of Varying Dosages of Progestogen in Silastic Vaginal Rings," Fertil. Steril, 21, 99 (1970); and Mishell, Footnote 13, infra.
Stumpf, P. G., et al, "Development of a Vaginal Ring for Achieving Physiologic Levels of 17b-estradiol in Hypoestrogenic Women," J. Clin. Endocrinol. Metab., 54, 208 (1982).
Yen, S. S. C., et al, "Circulating Estradiol, Estrone and Gonadotropin Levels Following the Administration of Orally Active 17b-estradiol in Postmenopausal Women," J. Clin. Endocrinol. Metab., 40, 518 (1975).
Langren, B. M. et al, "Hormonal Profile of the Cycle in 68 Normally Menstruating Women," Acta Endocrinologica 94, 89 (1980).
Csapo, Am J. Obstet. Gynecol. 115. 759 (1973).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for producing an in vivo environment suitable for human e does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing an in vivo environment suitable for human e, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing an in vivo environment suitable for human e will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1658084

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.