Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Reexamination Certificate
2008-03-14
2009-08-04
Witherspoon, Sikarl A (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
C568S830000, C568S914000
Reexamination Certificate
active
07569735
ABSTRACT:
A method for producing alcohols which comprises reducing esters or lactones with hydrogen gas in the presence of a catalyst comprising (i) a ruthenium compound, (ii) a monodentate monophosphine or a bidentate bisphosphine, and (iii) an amine. Examples of the catalyst include a ruthenium (Ru) complex represented by the formula:RuX1X2(LP)m(LN)n[X1and X2each represent an anionic ligand, LPrepresents a phosphine ligand, m is 1 when LPis bidentate, while m is 2 when LPis monodentate, LNrepresents an amine ligand, and n is 1 when LNis bidentate, while n is 2 when LNis monodentate.] and a catalyst comprising an amine and a ruthenium (Ru) complex of the formula: RuX1X2(LP1)r[LP1represents a monophosphine ligand and r is 3 or 4.].
REFERENCES:
patent: 2001-247499 (2001-09-01), None
patent: 2004-238306 (2004-08-01), None
patent: 2004-300131 (2004-10-01), None
patent: 2005-524704 (2005-08-01), None
patent: 11-189600 (1999-07-01), None
patent: WO 2006/106483 (2006-10-01), None
patent: WO 2006/106484 (2006-10-01), None
Grey, R., et al., “Homogeneous Catalytic Hydrogenation of Carboxylic Acid Esters to Alcohols”, J.C.S. Chem. Comm., 1980, pp. 783-784.
Nomura, K., et al., “Direct synthesis of 2-phenylethanol by hydrogenation of methyl phenylacetate using homogeneous ruthenium-phosphine catalysis under low hydrogen pressure”, Journal of Molecular Catalysis A: Chemical, 2001, pp. 345-349, vol. 166, Elsevier.
Zhang, J., et al., “Efficient Homogeneous Catalytic Hydrogenation of Esters to Alcohols”, Angewandte Chemie Int. Ed., 2006, pp. 1113-1115, vol. 45, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Greene, T., et al., Protective Groups in Organic Synthesis 2nd Edition, 1991, John Wiley & Sons, Inc.
Inorganic Syntheses, 1970, vol. 12, p. 238.
Inorganic Syntheses, 1970, vol. 17, p. 75.
Kitamura, M., et al., “Asymmetric Hydrogenation of 3-OXO Carboxylates Using BINAP-Ruthenium Complexes: (R)-(-)-Methyl 3-Hydroxybutanoate (Butanoic acid, 3-hydroxy-, methyl ester, (R)-)”, Org. Synth., 1993, pp. 1-13.
European Search Report issued in European Patent Application No. EP 08 15 2538, mailed Jul. 24, 2008.
Saudan, L., et al., “Dihydrogen Reduction of Carboxylic Esters to Alcohols under the Catalysis of Homogeneous Ruthenium Complexes: High Efficiency and Unprecedented Chemoselectivity”, Angew. Chem. Int. Ed., Aug. 2007, pp. 7473-7476, vol. 46.
Teunissen, H., et al., “Homogeneous ruthenium catalyzed hydrogenation of esters to alcohols”, Chem. Commun., Jan. 1998, 1367-1368, vol. 1998.
Ino Yasunori
Kuriyama Wataru
Yoshida Akifumi
McDermott Will & Emery LLP
Takasago International
Witherspoon Sikarl A
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