Method for producing acylated peptides

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Chemical aftertreatment – e.g. – acylation – methylation – etc.

Reexamination Certificate

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Details

C530S303000, C530S308000, C530S333000, C530S402000, C436S086000, C436S090000

Reexamination Certificate

active

10671260

ABSTRACT:
The present invention provides a method for acylating one or more amino groups of a peptide where the acylation reaction is to be performed in an aqueous mixture containing less than 10% w/w aprotic polar solvent.

REFERENCES:
patent: 3950517 (1976-04-01), Lindsay et al.
patent: 5905140 (1999-05-01), Hansen
patent: 6451974 (2002-09-01), Hansen
patent: 1227 107 (2002-07-01), None
patent: 95/07931 (1995-03-01), None
patent: 98/02460 (1998-01-01), None
patent: 98/08871 (1998-03-01), None
patent: 98/08872 (1998-03-01), None
patent: 99/43708 (1999-09-01), None
patent: 00/55119 (2000-09-01), None
Zivanovic et al., Biomedical Chromatography, vol. 14, pp. 56-57, 2000.

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