Method for producing aclacinomycins A, B, Y using Strepomyces la

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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43525235, 435886, 536 64, C07H 1704, C07H 15244, C12N 120, C12P 1956

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054847125

ABSTRACT:
Disclosed herein are a novel strain of Streptomyces and a method for the production of aclacinomycins A, B, Y and aglycone thereof by cultivating the same. Streptomyces lavendofoliae DKRS(KCTC 0092BP) of the present invention is capable of producing aclacinomycins A, B, Y and aglycone with higher yield. Further, it is possible to selectively produce aclacinomycin A or Y by adjusting pH of the cultured broth of Streptomyces lavendofoliae DKRS to 4.4 or 4.6 with acetate buffer or hydrochloric acid, respectively.

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ATCC Catalogue of Bacteria and Bacteriophages, 18th edition, Editors--Gherna et al., cover, copyright page and p. 335 (pub. 1992).

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